Treatment of Recurrent or Hormone-Resistant Prostate Cancer

For information about the treatments listed below, see the Treatment Option Overview section.

Standard treatment of recurrent or hormone-resistant prostate cancer may include the following:

• Hormone therapy.
• Chemotherapy for patients already treated with hormone therapy.
• Biologic therapy with sipuleucel-T for patients already treated with hormone therapy.
• External radiation therapy.
• Prostatectomy for patients already treated with radiation therapy.
• Alpha emitter radiation therapy.
• PARP inhibitor therapy for patients already treated with hormone therapy who have mutations in certain genes, such as BRCA1 or BRCA2.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.